Ms. Shreya Agarwal | Biomedical | Best Researcher Award

Ms. Shreya Agarwal | Biomedical | Best Researcher Award

Shreya Agarwal at University of Freiburg, Germany

Profiles

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Academic Background

Ms. Shreya Agarwal is a dedicated Life Scientist with a Master’s in Neuroscience and a passion for advancing our understanding of the brain. With substantial experience in laboratory research, she excels in data analysis, microscopy, molecular biology, and genetics. Known for her strong organizational skills and ability to manage multiple projects with precision, Shreya is committed to contributing to her team’s success and taking on new challenges.

Education

Master of Science (M.Sc.) in Molecular and Translational Neurosciences
University of Ulm, Germany (2021)
Thesis: “Study of the mutation KIF5A in ALS, which promotes protein aggregation”

Bachelor of Science (B.Sc.) in Neurosciences
Amity University, Noida, India (2019)
Thesis: “The role of chronic hypobaric hypoxia in the development of cognitive impairment”

Work Experience

PhD Student, Biomikrotechnik
Institut für Mikrosystemtechnik – IMTEK, Albert-Ludwigs-Universität Freiburg (Since 10.2023)
Researching network development and spatial embedding of inhibitory neurons.

Research Associate
Institute of Anatomy and Cell Biology, University of Ulm (01.2022 – 03.2023)
Investigated synaptic aging in Alzheimer’s and ALS; led tutoring and scientific discussions.

Research Assistant
Institute of Anatomy and Cell Biology, University of Ulm (01.2021 – 04.2021)
Assisted in experiments, maintained research records, and implemented data analysis software.

Training and Internship
Center for Clinical Research, University Clinic for Neurology, Ulm (10.2020 – 11.2020)
Studied clinical drug development and principles of pharmacokinetics.

Student Research Intern
Institute for Physiological Chemistry, University of Ulm (08.2020 – 10.2020)
Analyzed mouse models for NF kappa B expression and receptor tyrosine kinase investigation.

📚 Certifications

FELASA – Laboratory Animal Science Course (11.2023)
Project Management by IGradU (02.2023)
Scientific Writing and Presentation Skills (IGradU, 2022)
Writing in the Sciences by Stanford (07.2021)
Drug Discovery and Development by UC San Diego (12.2020)

🏆 Awards

STIBET Scholarship by Ulm University and DAAD (2020 – 2021)

🔧 Skills

Cell culture techniques, qPCR, Western Blot, Immunocytochemistry
Data analysis software including MATLAB, GraphPad Prism, ImageJ

Publications

Current status of drug targets and emerging therapeutic strategies in the management of Alzheimer’s disease
  • Authors: Shampa Ghosh, Shantanu Durgvanshi, Shreya Agarwal, Manchala Raghunath, Jitendra K Sinha
  • Journal: Current neuropharmacology
  • Year: 2020
Long-Term Potentiation
  • Authors: Jitendra Kumar Sinha, Shreya Agarwal, Shampa Ghosh
  • Year: 2022
Pituitary Gland
  • Authors: S Ghosh, S Durgvanshi, S Agarwal, JK Sinha
  • Journal: Encyclopedia of Animal Cognition and Behavior
  • Year: 2019

Dr. Weijian Ye | Biomedical | Best Researcher Award

Dr. Weijian Ye, Biomedical, Best Researcher Award

Doctorate at The First Affiliated Hospital of Jinan University, China

Professional Profile

Summary:

Dr. Weijian YE is a distinguished researcher in the field of Chemical Genomics, with a Ph.D. from Peking University and a Bachelor’s degree from Guangzhou University of Chinese Medicine. With a strong background in Pharmaceutical Engineering, Dr. YE has made significant contributions to biomedical research, particularly in the development of PET tracers and radio pharmacy.

👩‍🎓Education:

  • Ph.D. in Chemical Genomics (Advisor: Prof. LEE, Chi-Sing)
    Peking University, Beijing, China
    Sep. 2014 – Jun. 2019
  • Bachelor’s Degree in Pharmaceutical Engineering (Advisor: Prof. WANG, Tao)
    Guangzhou University of Chinese Medicine, Guangzhou, China
    Sep. 2010 – Jun. 2014

🧬 Work Experience:

Senior Research Fellow
Center of Cyclotron and PET Radiopharmaceuticals, Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou
Sep. 2021 – Present

  • Leading research in radio synthesis, PET tracer development, translational medicine, and clinical research.
  • Developing synthetic routes for complex molecules and managing radiopharmaceutical projects from development to cGMP production.
  • Collaborating with departments for clinical research on novel PET tracers for neurological disorders and other diseases.

Post-doctoral Research Fellow (Supervisor: Prof. XU, Hao)
Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou
Jul. 2019 – Jul. 2021

  • Trained in radiochemistry, focusing on synthesizing and managing radioisotopes for pharmaceutical quality and safety.
  • Applied research in clinical translational medicine, bridging lab work to clinical applications.

🔬 Research Experience

 A.Development of PET Tracers/Radio Pharmacy
  1. Norepinephrine Transporter Targeted Tracer 18F-mFBG
    • Optimized labeling conditions, achieving a 17.8% radiochemical yield and >97% radiochemical purity within 70 mins.
    • Established SOP for clinical production, producing over 30 batches for more than 200 patients.
  2. Multi-functional Imaging Probe for Cu(II)
    • Designed and synthesized Cu(II)-specific probes for fluorescence and 19F MR imaging.
    • Applied the 18F-isotopologue to PET imaging in cynomolgus macaques.
  3. Vasopressin 1a Receptor Targeted Tracer
    • Developed an F-18 labeled PET tracer with high affinity for V1a receptor.
    • Conducted PET imaging and kinetic modeling studies in rhesus monkeys.
  4. TSPO Polymorphism-insensitive PET Tracers
    • Synthesized ligands for TSPO, demonstrating low sensitivity to TSPO rs6971 polymorphism.
    • Conducted PET imaging studies in rhesus monkeys and MCAO animal models.
  5. 11C-labeled Tracers for mGlu2 and FAAH
    • Contributed to the development and analysis of 11C-labeled PET tracers for mGlu2 and FAAH.
  6. New Synthons and Radiolabeling Strategies
    • Synthesized [18F]difluorocarbene and [18F]fluoro-[di-deutero]methyl tosylate, implementing automated radiolabeling programs.
B. Development of Fluorescent Probes
  1. Eu(III) Complex as Fluorescent Probe for Paralytic Shellfish Toxins
    • Designed and characterized europium complexes, proposing binding mechanisms using ion mobility mass spectrometry.
  2. Fluorescent Chemosensors for Polyamines
    • Synthesized TPE-conjugated pentiptycene derivatives, applied for spermine detection in artificial urine.
  3. Fluorescent Probes and 1H/19F MRI Contrast Agents for EBNA1 and EBV
    • Designed and synthesized Eu(III) and Gd(III) complexes for EBNA1, evaluating magnetic resonance properties.
C. Organic Syntheses
  1. Total Synthesis of Natural Product (±)-basiliolide B and Its Analogues
    • Performed a 15-step synthesis sequence, including large-scale reactions.
  2. Regioselective Pd-catalyzed (3+2) Cycloaddition of 2-pyrones with Vinylcyclopropanes
    • Achieved high yields and regioselectivity, broadening substrate scope for synthesis.

Publications Top Noted:

Paper Title: A PET-based radiomics nomogram for individualized predictions of seizure outcomes after temporal lobe epilepsy surgery
  • Authors: Huanhua Wu, Kai Liao, Zhiqiang Tan, Chunyuan Zeng, Biao Wu, Ziqing Zhou, Hailing Zhou, Yongjin Tang, Jian Gong, Weijian Ye, Xueying Ling, Qiang Guo, Hao Xu
  • Journal: Seizure: European Journal of Epilepsy
  • Volume: 119
  • Pages: 17-27
  • Year: 2024
Paper Title: Recent developments on PET radiotracers for TSPO and their applications in neuroimaging
  • Authors: Lingling Zhang, Kuan Hu, Tuo Shao, Lu Hou, Shaojuan Zhang, Weijian Ye, Lee Josephson, Jeffrey H Meyer, Ming-Rong Zhang, Neil Vasdev, Jinghao Wang, Hao Xu, Lu Wang, Steven H Liang
  • Journal: Acta Pharmaceutica Sinica B
  • Volume: 11
  • Pages: 373-393
  • Year: 2021
  • Citations: 114
Paper Title: Positron emission tomography in the neuroimaging of autism spectrum disorder: a review
  • Authors: Zhiqiang Tan, Huiyi Wei, Xiubao Song, Wangxiang Mai, Jiajian Yan, Weijian Ye, Xueying Ling, Lu Hou, Shaojuan Zhang, Sen Yan, Hao Xu, Lu Wang
  • Volume: 16
  • Pages: 806876
  • Year: 2022
  • Citations: 14
Paper Title: Sensitive and responsive pentiptycene-based molecular fluorescence chemosensor for detection of polyamines
  • Authors: Junrong Huang, Weijian Ye, Shuai Zha, Yezi Tao, Min Yang, Ke Huang, Jiqiang Liu, Yan-Ho Fung, Yang Li, Penghao Li, Lizhi Zhu, Chi-Sing Lee
  • Journal: Journal of Luminescence
  • Volume: 232
  • Pages: 117856
  • Year: 2021
  • Citations: 12
Paper Title: Recent developments on the application of molecular probes in multiple myeloma: Beyond [18F] FDG
  • Authors: Shaojuan Zhang, Jingjie Shang, Weijian Ye, Tianming Zhao, Hao Xu, Hui Zeng, Lu Wang
  • Volume: 10
  • Pages: 920882
  • Year: 2022
  • Citations: 1

 

Pritam-Ghosh-Chemical Biology Award-Best Researcher  

Assist Prof Dr. Pritam-Ghosh-Chemical Biology Award-Best Researcher  

Vellore Institute of Technology-India 

Author Profile

Early Academic Pursuits

Assist Prof Dr. Pritam Ghosh embarked on his academic journey with a profound interest in chemistry, earning a Bachelor of Science in Chemistry (Hons.) from Visva Bharati (Central University), West Bengal, India. Building upon this foundation, he pursued a Master of Science degree with specialization in Inorganic Chemistry from the same institution. Driven by a passion for research, Ghosh furthered his academic pursuits by pursuing a Ph.D. from Jadavpur University and CSIR-CMERI, West Bengal, India. Under the guidance of esteemed mentors such as Dr. Partha Roy and Dr. P. Banerjee, he delved into the realm of chemical sensing, exploring the synthesis of non-innocent small molecules and transition metal complexes for various applications.

Professional Endeavors

Assist Prof Dr. Ghosh's professional journey reflects a commitment to interdisciplinary research and academic excellence. He garnered valuable postdoctoral experience at esteemed institutions such as Humboldt Universität zu Berlin, Germany, and Technion-Israel Institute of Technology, Israel. Additionally, he served as a Senior Assistant Professor in the Chemistry Division at VIT-Chennai, India, showcasing his dedication to both research and education.

Contributions and Research Focus On Chemical Biology Award

Assist Prof Dr. Ghosh's research focuses on the intersection of chemistry and biology, with an emphasis on chemical sensing, metal-ion recognition, and peptide design. His pioneering work includes the synthesis of peptoids and metallopeptoids for versatile applications in chemical biology. Furthermore, he has made significant contributions to supramolecular chemistry, elucidating the control over supramolecular architectures and their potential applications.

Accolades and Recognition

Assist Prof Dr. Pritam Ghosh contributions to the field of chemistry have been widely recognized through prestigious awards and fellowships. Notable accolades include the Newton International Fellowship, awarded by The Royal Society, UK, and the Lady Davis Postdoctoral Fellowship at Technion-Israel Institute of Technology, Israel. His research has also been acknowledged with best poster awards at international conferences and sponsorship from esteemed organizations such as the Society of Biological Inorganic Chemistry.

Pritam Ghosh stands as a beacon of excellence in the realm of Chemical Biology, earning the prestigious Chemical Biology Award for their remarkable contributions to scientific inquiry. With an unparalleled dedication to advancing knowledge at the intersection of chemistry and biology, Ghosh's work epitomizes innovation and interdisciplinary collaboration.

Impact and Influence

Assist Prof Dr. Ghosh's research has made a significant impact on the fields of chemical biology and materials science. His innovative work in chemical sensing and metal-ion recognition has the potential to revolutionize various applications, including biomedical diagnostics and environmental monitoring. Furthermore, his collaborations and publications demonstrate a commitment to advancing scientific knowledge and fostering interdisciplinary research collaborations.

Through pioneering research endeavors, Ghosh has achieved significant milestones in biomolecular chemistry, unveiling novel methodologies and pushing the boundaries of scientific exploration. Their relentless pursuit of excellence has led to breakthroughs in understanding molecular interactions, cellular processes, and disease mechanisms, thereby paving the way for transformative advancements in biomedical diagnostics and therapeutic strategies.

Legacy and Future Contributions

As Assist Prof Dr. Ghosh continues his academic and research endeavors, his legacy is poised to inspire future generations of scientists. His interdisciplinary approach and innovative methodologies pave the way for groundbreaking discoveries in chemistry and biology. Moving forward, Ghosh envisions leveraging his expertise to address pressing global challenges and contribute to the advancement of scientific knowledge and technological innovation.

Citations

  • Citations     2693
  • h-index           26
  • i10-index        42

Notable Publication