Dr. Rainer Hubmann | Biomedical and Healthcare Applications | Best Researcher Award

Dr. Rainer Hubmann | Biomedical and Healthcare Applications | Best Researcher Award

Doctorate at Red Cross | Austria

Mag. Dr. Rainer Hubmann embarked on his academic journey at the University of Vienna, earning his master’s degree in Biology/Genetics in 1996. During this time, he became an active member of the Cell Cycle Club under the leadership of Kim Nasmyth at the Research Institute of Molecular Pathology (IMP). His passion for molecular biology led him to pursue his Ph.D. at the Medical University of Vienna, where he focused on the regulation of CD23 in Chronic Lymphocytic Leukemia (CLL), completing it in 2002.

Professional Profiles

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🎓Education and Academic Background

Dr. Rainer Hubmann’s distinguished academic journey began at the University of Vienna, where he earned a Master’s degree in Biology and Genetics (1987–1996). During this time, he joined the prestigious Cell Cycle Club, led by Kim Nasmyth, sharpening his focus on cell cycle research. He pursued his Ph.D. thesis (1997–2002) at the Medical University of Vienna (MUW), investigating the Regulation of CD23 in Chronic Lymphocytic Leukemia (CLL). His postdoctoral work from 2002 to 2011 extended into pioneering studies on NOTCH2 regulation and the characterization of CLL stem cells. In 2022, he assumed the role of Group Leader and Senior Scientist at the Division of Hematology and Hemostaseology, MUW, further solidifying his leadership in hematological research.

🔬 Research and Innovation

Dr. Hubmann’s research has made groundbreaking strides in NOTCH signaling and its implications in cancer. His work elucidates the central role of NOTCH2 signaling in CLL leukemogenesis, uncovering vital mechanisms of disease progression. He has identified GLIOTOXIN as a potent therapeutic NOTCH2/CSL transactivation inhibitor, presenting it as a promising alternative to conventional γ-secretase inhibitors. Furthermore, he discovered a tumor-suppressor role for NOTCH3 signaling in CLL, revealing its therapeutic potential. Dr. Hubmann’s studies have highlighted the recurring NOTCH2ΔNRR gain-of-function (GOF) mRNA deletions as potentially disease-defining genetic lesions in CLL. His innovative research also explores somatic recombination involving ancient and recent NOTCH2 gene variants, addressing hereditary, geographic, and gender-based variations.

🧪 Patents and Innovations

Dr. Hubmann’s contributions to translational medicine are protected by several patents. These include Gliotoxin for the treatment of NOTCH2-associated malignancies (WO/2006/135949; US Patent No 7,981,878) and NOTCH21A01/1a4-RFLP as a leukemia/tumor predisposition detection tool (MUW Tech-ID: 835.19). His patented innovations underscore his role in translating basic research into clinical applications.

💡 Technical Expertise

Dr. Hubmann possesses advanced technical skills pivotal to hematology and oncology research. His expertise includes gene expression and silencing techniques such as retroviral vectors and siRNA-mediated gene silencing. He is proficient in molecular analysis, including RT-PCR, Northern & Western blotting, and RNA-seq sequence analysis. His work extends to drug screening models, xenograft mouse models, and developing diagnostic tools for personalized medicine. His ability to blend bioinformatics with preclinical studies further enhances his contributions to the field.

💵 Funding and Grants

Over his career, Dr. Hubmann has secured significant funding for his research. Notable grants include FWF P15100 (2001) for studying the Regulation and Function of NOTCH2 in CLL, and ÖNB Jubiläumsfonds (2002, 2004) for exploring NOTCH2 in leukemogenesis. His work on GLIOTOXIN’s therapeutic potential was supported by Initiative Krebsforschung (2013), while his recent studies on NOTCH2ΔNRR deletions were funded by the Fellinger Krebsforschungsfonds (2022). These funding milestones reflect the impact and importance of his research.

🏆 Awards and Recognition

Dr. Hubmann’s outstanding contributions to medical research have earned him numerous accolades. In 1999, he received the Aventis Stiftung Award for his work on fibroblast growth factor in Hairy Cell Leukemia. His innovative findings on interferon-alpha in Hairy Cell Leukemia earned the Erste Bank Preis in 2001. In 2005 and 2010, he was awarded the Sanofi-Aventis Prize for breakthroughs in cancer therapy and PI3-K/Akt/CK2 signaling. Additionally, the Paracelsus Medical University Award (2008) recognized his research on TGF-β in Radon therapy for Ankylosing Spondylitis patients.

🏢 Professional Memberships

Dr. Hubmann is an esteemed member of the Austrian Society for Hematology and Oncology (ÖGHO). He serves as the Vice Coordinator of the Comprehensive Cancer Center Vienna (CCC) Research Cluster, focusing on Microenvironment, Vasculature, and Metastasis, underscoring his leadership in advancing cancer research.

🎓 Teaching and Mentorship

Since 1998, Dr. Hubmann has played a pivotal role in teaching and mentoring young scientists. He leads specialized courses, including Molecular Biology in Hematology-Oncology and Clinical and Experimental Hematology, since 2001. His dedication extends to supervising Ph.D. and diploma students, nurturing the next generation of researchers and clinicians.

Publications Top Noted📚 

Targeting Nuclear NOTCH2 by Gliotoxin Recovers a Tumor-Suppressor NOTCH3 Activity in CLL Cells

Authors: Rainer Hubmann

Journal: Cells

Year: 2020

UGT2B17 modifies drug response in chronic lymphocytic leukaemia

Authors: Rainer Hubmann

Journal: British Journal of Cancer

Year: 2020

Combined approach for characterization and quality assessment of rabbit bone marrow-derived mesenchymal stem cells intended for gene banking

Authors: Rainer Hubmann

Journal: New Biotechnology

Year: 2020

Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL

Authors: Rainer Hubmann

Journal: Nature Chemical Biology

Year: 2019

Critical assessment of the efficiency of CD34 and CD133 antibodies for enrichment of rabbit hematopoietic stem cells

Authors: Rainer Hubmann

Journal: Biotechnology Progress

Year: 2018

Ipseeta Mohanty Ray | Biomedical | Excellence in Research

Prof Dr. Ipseeta Mohanty Ray | Biomedical | Excellence in Research

Prof Dr. Ipseeta Mohanty Ray at MGM Medical College & Hospital, India

Profile👨‍🎓

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Publications

Influence of Types of Media and Modes of Therapeutic Ultrasound on Drug Absorption in Phonophoresis: A Comparative Experimental Study on Rabbits
  • Authors: Sreeraj, S.R., Bellare, B., Ray, I.
    Journal: Research Journal of Pharmacy and Technology
    Year: 2023
Adverse Drug Monitoring in the Psychiatry Outpatient Department in a Tertiary Care Hospital – A Pilot Study
  • Authors: Gandhi, M., Zaveri, H., Ray, I., Gildhiyal, R.
    Journal: Biomedical and Pharmacology Journal
    Year: 2022
Evaluation of Analgesic Activity of Levofloxacin in Human Experimental Pain Model
  • Authors: Shetty, R., Chaudhari, S., Jadhav, P., Ray, I., Deshmukh, Y.
    Journal: Journal of Basic and Clinical Physiology and Pharmacology
    Year: 2015
Assessment of Usage of Antibiotics and Their Pattern of Antibiotic Sensitivity Test Among Childhood Fever
  • Authors: Suman, R.K., Ray, I.M., Mohanty, N.C., Mukhia, R.K., Deshmukh, Y.A.
    Journal: International Journal of Pharmacy and Pharmaceutical Sciences
    Year: 2014

Ms. Zakya Mhamdi | Biomedical | Best Researcher Award

Ms. Zakya Mhamdi | Biomedical | Best Researcher Award

Zakya Mhamdi at Moulay Ismail Univirsity, Morocco

Profiles

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Research Gate

📚 Summary

Ms. Zakya M’hamdi is a dedicated and detail-oriented PhD student in Fundamental and Applied Sciences with a specialization in Organic Chemistry. Her research focuses on the valorization of medicinal plants, emphasizing their antioxidant, antibacterial, and anticorrosive properties. Zakya’s academic journey is marked by significant research contributions and practical experiences in both local and international settings.

Education

  • 2023-2024: Doctorate in Fundamental and Applied Sciences (Organic Chemistry) – Université Moulay Ismail, Meknès, Morocco
  • 2020-2021: Master in Materials and Molecular Engineering (Molecular Chemistry and Natural Substances) – Université Moulay Ismail, Meknès, Morocco
  • 2018-2019: Bachelor’s in Fundamental Chemistry (Organic Chemistry) – Université Moulay Ismail, Meknès, Morocco
  • 2017-2018: DEUG in Chemistry – Université Moulay Ismail, Meknès, Morocco
  • 2015-2016: Baccalaureate in Experimental Sciences (Physical Sciences) – Lycée Amir Moulay Abdallah, Er-Rachidia, Morocco

💼 Professional Experience

  • 2023: Research Intern at CHIBIOFARAM Laboratory, University of Messina, Italy
  • 2023: Research Intern in Organometallic Materials Engineering Laboratory, Faculty of Sciences, University Sidi Mohamed Ben Abdellah, Fès, Morocco
  • 2022: Assisted in preparing practical lab sessions for Organic Chemistry modules at Université Moulay Ismail, Meknès, Morocco
  • 2021: Member of organizing committee for ICPAS 2022 and ICME6-2022 conferences; supervised student projects at Université Moulay Ismail, Meknès, Morocco

🔬 Research Interests

  • Medicinal Plants: Chemical composition and bioactivity of plants like Pelargonium graveolens and Urtica dioica
  • Analytical Techniques: Mastery in RX, IR, FX, UV, RMN, HPLC, CPG, CCM, ATG/ATD, SAA
  • Environmental Chemistry: Investigation of corrosion inhibitors and environmental degradation prevention
  • Antioxidant & Antibacterial Activities: Evaluation of plant extracts for their potential health benefits and industrial applications

🔧 Skills

  • Scientific Techniques: Proficient in various analytical and extraction techniques
  • Technical Tools: Experienced with Microsoft Word, Excel, PowerPoint, and Origin

 

Publications

Chemical composition and antibacterial activity of essential oil of Pelargonium graveolens and its fractions

  • Authors: M’hamdi, Z., Bouymajane, A., Riffi, O., Elhourri, M., Amechrouq, A.
  • Journal: Arabian Journal of Chemistry
  • Year: 2024

Study of the chemical composition and evaluation of the antioxidant and antimicrobial activity of Taxus baccata L.

  • Authors: Riffi, O., Reda Kachmar, M., M’hamdi, Z., Chakir, S., Amechrouq, A.
  • Journal: Arabian Journal of Chemistry
  • Year: 2023

Investigation into the Prevention of Environmental Degradation of Mild Steel in a 1M HCl Solution Using Extracts Derived from Pelargonium graveolens

  • Authors: M’hamdi, Z., Riffi, O., Ettahiri, W., Taleb, M., Amechrouq, A.
  • Journal: Journal of Bio- and Tribo-Corrosion
  • Year: 2023

Thermal analysis and determination of the heavy metal content of the plant Urtica Dioica L. by atomic absorption spectroscopy

  • Authors: M’hamdi, Z., Sabiri, M., Elhourri, M., Amechrouq, A.
  • Journal: Moroccan Journal of Chemistry
  • Year: 2023

Comparative Study of the Chemical Composition and Antioxidant Activities of the Essential Oil of Pelargonium graveolens from the Four Regions of Morocco

  • Authors: Zakya, M., Elhourri, M., Kachmar, M.R., Maryam, S., Ali, A.
  • Journal: Indian Journal of Agricultural Biochemistry
  • Year: 2022

Mrs. Anna Dziewulska | Biomedical | Best Researcher Award

Mrs. Anna Dziewulska | Biomedical | Best Researcher Award

Anna Dziewulska at Pomeranian Medical University, Poland

Profiles

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Summary:

Mrs. Anna Dziewulska is an Assistant Professor at the Department of Interdisciplinary Dentistry at Pomeranian Medical University, Szczecin, Poland. With extensive experience in both academic and clinical settings, she is dedicated to advancing dental education and patient care.

Education

Mrs. Dziewulska earned her degree in Dentistry from the Medical University in Lublin, Poland (2002). She completed her doctoral studies at the same institution, defending her dissertation on the presence of selected elements in saliva in patients treated for oral cancer (2009). She later specialized in Conservative Dentistry with Endodontics, obtaining her specialist title in 2022 after completing a specialization course at the University Dental Clinic in Szczecin.

💼 Professional Experience

Since 2009, Mrs. Dziewulska has served as an Assistant Professor at the Department of Interdisciplinary Dentistry and a practicing dentist at the University Dental Clinic in Szczecin. Prior to this, she worked as a dentist in various dental offices in Lublin from 2003 to 2007.

🔬 Research Interests

Dr. Dziewulska’s research interests focus on conservative dentistry and endodontics, with a particular emphasis on the role of elements in saliva in the context of oral cancer treatment

 

Publications

Oral Health in Patients Hospitalized Because of Ischemic Stroke

  • Authors: Dziewulska, A., Pawlukowska, W., Zawiślak, A., Masztalewicz, M., Grocholewicz, K.
  • Journal: Journal of Clinical Medicine
  • Year: 2024
  • Authors: Pawlukowska, W., Baumert, B., Meller, A., Nowacki, P., Masztalewicz, M.
  • Journal: Journal of Clinical Medicine
  • Year: 2022

Effect of nano-hydroxyapatite and ozone on approximal initial caries: a randomized clinical trial

  • Authors: Grocholewicz, K., Matkowska-Cichocka, G., Makowiecki, P., Trybek, G., Janiszewska-Olszowska, J.
  • Journal: Scientific Reports
  • Year: 2020

Salivary mineral composition in patients with oral cancer

  • Authors: Dziewulska, A., Janiszewska-Olszowska, J., Bachanek, T., Grocholewicz, K.
  • Journal: Magnesium Research
  • Year: 2013

Mr. Dimos Dimitrios Plakotaris | Biomedical | Best Researcher Award

Mr. Dimos Dimitrios Plakotaris | Biomedical | Best Researcher Award

Dimos Dimitrios Plakotaris at Aristotle University of Thessaloniki , Greece

Profile

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📋 Summary

Mr. Dimos Dimitrios Plakotaris is a newly graduated Mechanical Engineer specializing in the energy sector. With a keen interest in integrating artificial intelligence and machine learning into engineering, Dimos aims to enhance his academic and practical skills to develop innovative solutions in engineering projects.

Education

Mr. Dimos earned his Diploma in Mechanical Engineering from the Polytechnic School of Aristotle University of Thessaloniki in April 2024, with a focus on Energy. He graduated with a grade of 6.6 (Very Good). Prior to this, he completed his secondary education at 1st Lyceum of Mitilini, achieving an impressive graduation grade of 19.0/20.0.

💼 Work Experience

  • July 2021 – Aug 2021: Citrus Museum at Kambos Chios and cohousing café Perivoli
  • July 2020 – Aug 2020: Citrus Museum at Kambos Chios and cohousing café Perivoli

💻 Software Skills

  • Matlab: Intermediate level
  • Python: Intermediate level
  • AutoCAD: Advanced level
  • MS Office

🔬 Research Experience

Mr. Dimos Dimitrios Plakotaris conducted his diploma thesis titled “Recording, Analyzing, Mapping, and Modeling Air Quality Levels Using Low-Cost Sensors on Pedestrian Routes in the Urban Center of Thessaloniki” under the supervision of Professor K. Karatzas. This project involved data collection using low-cost sensors, data analysis and modeling in Python, prediction and data reconstruction with machine learning, and the design and execution of the experiment. This work culminated in the publication of the paper “Estimation of Particulate Matter Levels in City Center Pedestrian Routes with the Aid of Low-Cost Sensors” in the journal Atmosphere (2024).

 

Publications

Estimation of Particulate Matter Levels in City Center Pedestrian Routes with the Aid of Low-Cost Sensors

  • Authors: Dimos Dimitrios Plakotaris, Theodosios Kassandros, Evangelos Bagkis, Kostas Karatzas
  • Journal: Atmosphere
  • Year: 2024

Assoc Prof Dr. Maria Teresa Arias Loste | Biomedical | Best Researcher Award

Assoc Prof Dr. Maria Teresa Arias Loste, Biomedical, Best Researcher Award

Maria Teresa Arias Loste at Instituto de Investigación Marqués de Valdecilla, Spain

Professional Profile

🌟 Summary:

Assoc. Prof. Dr. María Teresa Arias Loste is a renowned Consultant Physician Specialist in Gastroenterology at the University Hospital Marqués de Valdecilla. With a solid academic background and extensive research experience, she has significantly contributed to the field of Gastroenterology, particularly in Non-Alcoholic Fatty Liver Disease (NAFLD) and Metabolic Associate Steatotic Liver Disease (MASLD).

🎓 Education:

  • Ph.D. in Biomedicine and Health Sciences, University of Cantabria, 2017
  • Master’s Degree in Hepatology, University of Alcalá and Autonomous University of Madrid, 2014
  • Bachelor of Medicine and Surgery, University of Zaragoza, 2005

💼 Professional Experience:

  • Consultant Physician Specialist in Gastroenterology, University Hospital Marqués de Valdecilla, 2012-present
  • Fellow Researcher, López Albo / Marqués de Valdecilla Research Institute Foundation, 2010-2012
  • Consultant Physician Specialist in Gastroenterology, Marqués de Valdecilla University Hospital, 2010
  • Resident Physician in Gastroenterology, University Hospital Marques de Valdecilla, 2006-2010

🔬 Research Interest:

Dr. Arias Loste’s research focuses on the immunological, genetic, and metabolic mechanisms of NAFLD and MASLD. She has been involved in numerous clinical trials and projects, including leading studies on the brain-liver axis in psychosis patients and innovative MASLD monitoring and telemedicine initiatives.

📖 Publications Top Noted:

Paper Title: Serum identification of at-risk MASH: The metabolomics-advanced steatohepatitis fibrosis
  • Authors: Noureddin, M., Truong, E., Mayo, R., Mato, J.M., Sanyal, A.J.
  • Journal: Hepatology
  • Year: 2024
  • Citations: 15
Paper Title: An international multidisciplinary consensus on pediatric metabolic dysfunction-associated fatty liver disease
  • Authors: Zhang, L., El-Shabrawi, M., Baur, L.A., George, J., Zheng, M.-H.
  • Journal: Med
  • Year: 2024
  • Citations: 1
Paper Title: Evaluation of metabolic dysfunction-associated steatotic liver disease (MASLD) terminology in different clinical settings
  • Authors: Iruzubieta, P., Santos-Laso, A., Arias-Loste, M.T., Calleja, J.L., Crespo, J.
  • Journal: Journal of Hepatology
  • Year: 2024
  • Citations: 1
Paper Title: Clinical and genetic factors involved in Porto-sinusoidal vascular disorder after oxaliplatin exposure
  • Authors: Puente, A., Fortea, J.I., Del Pozo, C., Bañares, R., Crespo, J.
  • Journal: Digestive and Liver Disease
  • Year: 2024
Paper Title: Immunological and senescence biomarker profiles in patients after spontaneous clearance of hepatitis C virus: gender implications for long-term health risk
  • Authors: Martín-Escolano, R., Vidal-Alcántara, E.J., Crespo, J., Jiménez-Sousa, M.Á., Fernández-Rodríguez, A.
  • Journal: Immunity and Ageing
  • Year: 2023
  • Citations: 1