Dr. Boon Seng-Soh-Video Analysis and Understanding-Best Researcher Award
Institute of Molecular and Cell Biology-Singapore
Author Profile
Early Academic Pursuits
Dr. Boon Seng Soh, Ph.D., commenced his academic journey with distinction, earning a B.Sc. with First Class Honours in Microbiology from the National University of Singapore. His pursuit of knowledge continued with a Ph.D. in Stem Cell and Developmental Biology from Imperial College London in 2010, focusing on the optimization of human embryonic stem cell culture and directing their differentiation toward the lung lineage. This early academic foundation laid the groundwork for his subsequent groundbreaking research.
Professional Endeavors
Dr. Soh's career trajectory has been marked by significant achievements. As an A*STAR Graduate Scholarship (Overseas) recipient, he completed his Ph.D. thesis under the cosupervision of Prof. Athanasios Mantalaris, Ph.D., and Prof. Bing Lim, MD, Ph.D. His postdoctoral experience at Harvard University, particularly in the laboratory of Prof. Kenneth Chien, MD, Ph.D, exposed him to the biology of multipotent cardiac stem cells, further shaping his clinically driven research focus.
Contributions and Research Focus
Throughout his research career, Dr. Soh has demonstrated a keen emphasis on understanding the molecular and cellular mechanisms underlying diseases. His expertise encompasses modeling human diseases of the heart and brain, with a specific focus on developing therapies. As the Principal Investigator at the Institute of Molecular and Cell Biology (IMCB), A*STAR, his work spans both in vitro and in vivo platforms for therapeutics development.
Accolades and Recognition
Dr. Soh's contributions to the field have not gone unnoticed. His impressive H-Index of 27 reflects the impact of his research. Additionally, his research papers have been published in high-impact journals, contributing to the scientific community's understanding of cardiovascular diseases and stem cell biology.
Impact and Influence
Dr. Soh's influence extends beyond his laboratory. As an Adjunct Assistant Professor at the Department of Biological Sciences, National University of Singapore, he plays a pivotal role in shaping the academic landscape. His diverse research experiences, including investigating diseased cardiac phenotypes in patients with Spinal Muscular Atrophy and developing therapeutics for myocardial infarction, highlight his commitment to addressing critical medical challenges.
Legacy and Future Contributions
Dr. Boon Seng Soh's legacy is characterized by his role in advancing the field of stem cell biology and disease modeling. His work on cardiac organoids and the application of machine learning analysis in characterizing arrhythmia showcases his innovative approach. As he continues his role as a Principal Investigator and Adjunct Assistant Professor, Dr. Soh is poised to make future contributions that further our understanding of human diseases and pave the way for novel therapeutic interventions.
Notable Publication
- Current RNA strategies in Treating Cardiovascular Diseases
- JAK2 as a surface marker for enrichment of human pluripotent stem cells-derived ventricular cardiomyocytes
- Site-directed deuteration of dronedarone preserves cytochrome P4502J2 activity and mitigates its cardiac adverse effects in canine arrhythmic hearts
- 3D Human Organoids: The Next “Viral” Model for the Molecular Basis of Infectious Diseases
- Translational stem cell therapy: vascularized skin grafts in skin repair and regeneration