Prof Dr. Michael Linnebacher | Healthcare Applications | Best Researcher Award

Prof Dr. Michael Linnebacher | Healthcare Applications | Best Researcher Award

Prof Doctorate at Universitätsmedizin Rostock, Germany 

Profiles

Scopus

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Summary:

Prof Dr. Michael Linnebacher, born on July 5, 1969, in Ottweiler, Germany, is a prominent researcher in molecular oncology and immunotherapy. He serves as the Laboratory and Research Director at the Clinic for General Surgery, University Medicine Rostock. Linnebacher’s career spans significant contributions to the understanding and treatment of gastrointestinal tumors, particularly focusing on immunotherapy and the role of microsatellite instability in cancer.

Education

Prof Dr. Linnebacher holds a Diploma in Biology from the University of Saarland (1996) and completed his PhD in Biology at the Technical University of Karlsruhe in 2001. His academic training includes extensive research on immunogenic neo-peptides and tumor antigens, setting a strong foundation for his career in oncology and immunotherapy.

💼 Professional Experience

  • 1996-1997: Research assistant, Heidelberg University Biochemistry Center
  • 1998-2001: PhD student, Institute of Immunology, Ruprecht-Karls-University Heidelberg
  • 2001-2005: Postdoctoral research, University Hospital Heidelberg, Department of Molecular Pathology
  • 2005-Present: Laboratory Director, Molecular Oncology and Immunotherapy, Clinic for General Surgery, University Medical Center Rostock
  • 2009: Venia legendi (Privatdozent)
  • 2010: Junior Professor for Immunology and Infectiology, University of Saarland
  • 2012: Professor for Translational Surgical Oncology and Biobanking, University of Lübeck
  • 2020-Present: Managing Director, BioBank Rostock; Member of the German Biobank Alliance

🔬 Research Interests

  • Immunotherapy and its applications in cancer treatment
  • Microsatellite instability and its role in tumor antigen development
  • Translational research in oncology
  • Biobanking and its role in cancer research and treatment

 

Publications

Peptide-stimulated T cells bypass immune checkpoint inhibitor resistance and eliminate autologous microsatellite instable colorectal cancer cells

  • Authors: Schwarz, S., Su, Z., Krohn, M., Schlosser, A., Linnebacher, M.
  • Journal: npj Precision Oncology
  • Year: 2024
  • Authors: Edelmann, M., Fan, S., De Oliveira, T., Rieken, S., Conradi, L.-C.
  • Journal: Cancer Research Communications
  • Year: 2024

Transcriptome-wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer

  • Authors: Mariella, E., Grasso, G., Miotto, M., Di Nicolantonio, F., Bardelli, A.
  • Journal: Molecular Oncology
  • Year: 2024

SKP2 promotes the metastasis of pancreatic ductal adenocarcinoma by suppressing TRIM21-mediated PSPC1 degradation

  • Authors: Yuan, J., Zhu, Z., Zhang, P., Gong, P., Zhang, X.
  • Journal: Cancer Letters
  • Year: 2024

A glutamatergic biomarker panel enables differentiating Grade 4 gliomas/astrocytomas from brain metastases

  • Authors: Lange, F., Gade, R., Einsle, A., Freiman, T.M., Kirschstein, T.
  • Journal: Frontiers in Oncology
  • Year: 2024

Dr. Yongkui Ren | Healthcare Applications | International Visionary in Computer Vision Award

Dr. Yongkui Ren | Healthcare Applications | International Visionary in Computer Vision Award

Doctorate at The First Affiliated Hospital of Dalian Medical University, China

Profile

Scopus

📋 Summary

Dr. Yongkui Ren, a distinguished cardiovascular specialist, is currently 38 years old. He serves as the Associate Chief Physician in the Department of Cardiovascular Medicine at The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Education

Dr. Ren obtained his MD from Capital Medical University in Beijing, China. He completed his Master’s and Bachelor’s degrees at China Medical University in Shenyang, China, specializing in cardiovascular research and clinical practice.

🩺 Professional and Teaching Experience

Dr. Ren’s medical career began as a resident doctor in the Department of Cardiovascular Medicine at The First Affiliated Hospital of Dalian Medical University. Over the years, he advanced to Attending Physician and currently holds the position of Associate Chief Physician. His extensive experience in cardiovascular medicine has made him a valuable asset to his department.

🏥 Professional Society Membership

Dr. Ren is an active member of the Hypertension Prevention and Control Professional Committee of the Liaoning Primary Health Association, contributing to advancements in hypertension management and control.

🔬 Research Experience

Dr. Ren’s research journey began during his Master’s degree, focusing on myocardial ischemia-reperfusion injury. He continued his research at The First Affiliated Hospital of Dalian Medical University, where he successfully applied for grants and participated in significant multi-center clinical trials. His recent work during his Ph.D. involves the analysis of medical big data using machine learning methods for cohort analysis and prediction.

🔭 Future Research Directions:

Dr. Ren aims to further investigate the mechanisms behind coronary artery calcification and its progression. He is also interested in identifying markers related to coronary calcification and exploring their mechanisms through basic research. Additionally, he plans to leverage advanced statistical methods, such as R language and machine learning, for data mining and participate in multi-center clinical trials.

 

Publications

Mediating Effect of the NLR on the Relationship between HbA1c and Left Atrial Stiffness in Overweight Patients with Hypertension

  • Authors: Zhang, R., Pan, Y., Ren, Y.K., Liu, Y., Jiang, Y.N.
  • Journal: American Journal of Hypertension
  • Year: 2024

Diagnostic accuracy of a novel optical coherence tomography-based fractional flow reserve algorithm for assessment of coronary stenosis significance

  • Authors: Pan, W., Wei, W., Hu, Y., Leng, X., Yin, D.
  • Journal: Cardiology Journal
  • Year: 2024

Predictive value of machine learning algorithm of coronary artery calcium score and clinical factors for obstructive coronary artery disease in hypertensive patients

  • Authors: Wang, M., Sun, M., Yu, Y., Ren, Y., Yin, D.
  • Journal: BMC Medical Informatics and Decision Making
  • Year: 2023

Triglyceride glucose index is associated with obstructive coronary artery disease in hypertensive patients

  • Authors: Pan, W., Ren, Y., Yang, F., Li, X., Yin, D.
  • Journal: Cardiovascular Diabetology
  • Year: 2023

Association of triglyceride glucose index levels ​​with calcification patterns and vulnerability of plaques: an intravascular ultrasound study

  • Authors: Yin, D., Wang, M., Liu, X., Ren, Y., Liu, J.
  • Journal: International Journal of Cardiovascular Imaging
  • Year: 2023