Mrs. Golnaz Atri Roozbahani | Prostate Cancer Research | Best Researcher Award
Jena University Hospital, Germany
Profiles
Ā Early Academic Pursuits
Mrs. Golnaz Atri Roozbahani embarked on her academic journey with aĀ Bachelorās degree in Cellular and Molecular Biology-GeneticsĀ fromĀ Shahid Chamran University of Ahvaz, Iran, where she graduated with distinction, achieving aĀ GPA of 17.94/20.00 (3.9/4.00). Her passion for genetics led her to pursue aĀ Masterās degree in Biology-GeneticsĀ atĀ Shahid Beheshti University, Tehran, Iran, where she conducted groundbreaking research onĀ single nucleotide polymorphism rs137853118 in spermatogenesis-associated 16 gene, which is linked to male infertility in the Iranian population. HerĀ academic excellenceĀ was recognized when she was awarded a direct admission to the MSc program without the necessity of an entrance exam.
Professional Endeavors
Mrs. Roozbahani has built an impressive professional portfolio, demonstrating her expertise across both academic and industrial settings. Currently, she serves as aĀ Lab Research Assistant at Jena University Hospital, Institute of Human Genetics, Germany, where she supervisesĀ bachelor and master studentsĀ in molecular genetics research. Previously, she worked as anĀ R&D Responsible at TBA Biomedical Company in Tehran, where she contributed to innovative biomedical advancements. Additionally, she has heldĀ various research assistant roles at Shahid Beheshti University of Medical Sciences and the Faculty of Life Sciences and Biotechnology, gaining extensive experience in molecular biology and genetics research.
Contributions and Research Focus
Mrs. RoozbahaniāsĀ doctoral research at Friedrich Schiller University Jena, Germany, under the supervision ofĀ Prof. Dr. rer. nat. Aria Baniahmad, is focused on theĀ biochemical and functional analysis of the novel androgen receptor antagonist C28 in human prostate cancer cells. Her work is crucial in understandingĀ prostate cancer treatment mechanisms, with potential applications in targeted therapies. In addition to cancer genetics, she has worked onĀ tumor spheroids, chromatin immunoprecipitation, cellular senescence, and protein interactions, which are key areas inĀ biomedical research.
Ā Impact and Influence
Through her diverse roles inĀ research and development, Mrs. Roozbahani has contributed significantly toĀ cancer research, genetic studies, and biomedical innovations. Her findings are instrumental in shaping the future ofĀ prostate cancer treatmentĀ and have the potential toĀ advance personalized medicine approaches. She has also mentored severalĀ graduate students, imparting her knowledge and fostering the next generation ofĀ scientists and researchers.
Ā Academic Citations and Recognitions
Her academic dedication has been recognized with multiple awards, including the prestigiousĀ DAAD (German Academic Exchange Service) Scholarship for doctoral studies in Germany (2021-present). She also ranked among theĀ top 2% of all applicants in the Nationwide University Entrance Exam in Iran, demonstrating her exceptional academic capabilities.
Ā Technical Skills and Expertise
- Cancer Research Methods: Xenograft mouse model studies, tumor spheroid generation, chromatin immunoprecipitation, and flow cytometry
- Molecular Biology Techniques: DNA, RNA, and protein extraction, cell culture, PCR variations (PCR-RFLP, ARMS-PCR, qRT-PCR), immunofluorescence, Western blotting
- Data Analysis and Bioinformatics: BD Accuri, GraphPad, MEGA, BioEdit, SNP STAT, and Microsoft Office Suite
Her technical expertise extends toĀ cloning, competent bacteria generation, and cell viability analysis, making her a well-rounded molecular biologist.
Teaching and Mentorship
In addition to her research, Mrs. Roozbahani has been actively involved inĀ mentorship and training. She has supervised and guidedĀ undergraduate and postgraduate students, helping them develop expertise inĀ molecular genetics and cancer research. Her ability to convey complex concepts in anĀ accessible and engaging mannerĀ has made her aĀ respected mentorĀ among students.
Ā Legacy and Future Contributions
With a strong foundation inĀ molecular genetics, oncology research, and biomedical innovations, Mrs. Roozbahani is poised to makeĀ significant contributions to cancer research and genetic therapeutics. Her work onĀ androgen receptor antagonistsĀ has the potential toĀ revolutionize prostate cancer treatments, and her commitment toĀ academic excellence, mentorship, and research innovation will continue to influence the field for years to come.
Publications
H2AJ Is a Direct Androgen Receptor Target Gene That Regulates Androgen-Induced Cellular Senescence and Inhibits Mesenchymal Markers in Prostate Cancer Cells
- Authors: Mehdi Heidari Horestani, Golnaz Atri Roozbahani, Aria Baniahmad
- Journal: Cancers
- Year: 2025
The protein composition of exosomes released by prostate cancer cells is distinctly regulated by androgen receptor-antagonists and-agonist to stimulate growth of target cells
- Authors: Golnaz Atri Roozbahani, Miriam Kokal-Ribaudo, Mehdi Heidari Horestani, Thanakorn Pungsrinont, Aria Baniahmad
- Journal: Cell Communication and Signaling
- Year: 2024
The clock gene BHLHE40 and atypical CCNG2 control androgen-induced cellular senescence as a novel tumor suppressive pathway in prostate cancer
- Authors: Mehdi Heidari Horestani, Golnaz Atri Roozbahani, Aria Baniahmad
- Journal: Journal of Experimental & Clinical Cancer Research
- Year: 2024
The oncogenic lncRNA MIR503HG suppresses cellular senescence counteracting supraphysiological androgen treatment in prostate cancer
- Authors: Julia Kallenbach, Mahdi Rasa, Mehdi Heidari Horestani, Golnaz Atri Roozbahani, Katrin Schindler, Aria Baniahmad
- Journal: Journal of Experimental & Clinical Cancer Research
- Year: 2024
The Novel Direct AR Target Gene Annexin A2 Mediates Androgen-Induced Cellular Senescence in Prostate Cancer Cells
- Authors: Kimia Mirzakhani, Mehdi Heidari Horestani, Julia Kallenbach, Golnaz Atri Roozbahani, Aria Baniahmad
- Journal: Biochemical Genetics
- Year: 2024